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Tracking Seizure cycles

Seer has initiated a human research project in collaboration with university and hospital partners. The aim is to understand the causes of daily and multi-day (weekly, monthly) cycles of seizures. 

CYcles Research

Our research, published in Lancet Neurology, showed that seizure cycles are common for both men and women with all types of epilepsy. We found over 80% of people have a circadian (daily) cycle, and over 50% of people have a cycle of one week or longer.

This study will monitor individuals’ seizure cycles in conjunction with a range of environmental, physiological and behavioural variables to discover candidate factors that are causally linked to seizure cycles. Data will be collected from mobile and wearable devices using the Seer App and connected smartwatches. Long-term metabolic data (such as hormone levels, or blood sugar) may also be monitored via capillary sampling at various points in an individual's cycle. 

Cyclic histograms of seizure onset show examples of seizure cycles recorded via mobile app

Cyclic histograms of seizure onset show examples of seizure cycles recorded via mobile app

Benefits

Discovering the environmental and biological drivers for seizure cycles can lead to a better understanding of the causes of seizures and may improve treatment by timing medication to suit individuals’ cycles. Participants are expected to benefit from a greater understanding of their seizure triggers and the use of smart devices to manage their epilepsy.

In the longer term, monitoring cycles of seizure likelihood will contribute to Seer’s goal to develop a personalised seizure gauge for people with epilepsy.

GET INVOLVED

If you are interested in learning more about this research, would like to get involved, or have patients with cyclic seizures who you would like to refer, please contact the principal investigator, Pip Karoly, or complete the form below.

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